Nasopharyngeal colonization and invasive disease are enhanced by the cell wall hydrolases LytB and LytC of Streptococcus pneumoniae.
BACKGROUND: Streptococcus pneumoniae is a common colonizer of the human nasopharynx Daily Cream and one of the major pathogens causing invasive disease worldwide.Dissection of the molecular pathways responsible for colonization, invasion, and evasion of the immune system will provide new targets for antimicrobial or vaccine therapies for this commo